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Next Generation Sequencing Facilitates Quantitative Analysis of Macrophage and Leukemia Stem Cell Transcriptomes in Mouse Iron-overload MLL-AF9 Acute Myeloid Leukemia

GSE226727 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/09/04 Platform GPL24247
Summary
The goals of this study aim to reveal functional and phenotypic diversity of Macrophage and Leukemia Stem Cell in response to the Iron-overloaded microenvironmental cues in mouse acute myeloid leukemia
Published in
Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia
Yang F, Luo S, Yang D et al. · Frontiers in immunology 2025 · PMID 40881683 · doi:10.3389/fimmu.2025.1626888
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Also filed as BioProject PRJNA941290 and SRA study SRP425866. Searching any of these in the dataset finder brings you back here.

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