YTHDF1 mitigates acute kidney injury via safeguarding m6A-methylated mRNAs in stress granules of renal tubules
DNA methylation · human · 29 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Samples
- 29 samples: 5 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE226787_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA941795 and SRA study SRP426040. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 15 samples.
How we read this: 5 replicated groups read from 29 sample titles; they account for 15 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7083755 NC1 input
- GSM7083756 NC2 input
- GSM7083757 NC3 input
- GSM7083758 OE1 input
- GSM7083759 OE2 input
- GSM7083760 OE3 input
- GSM7083761 NC1 IP
- GSM7083762 NC2 IP
- GSM7083763 NC3 IP
- GSM7083764 OE1 IP
- GSM7083765 OE2 IP
- GSM7083766 OE3 IP
- GSM7083767 RIP_Input
- GSM7083768 RIP_IP
- GSM7083769 H2O2_1 H2O2
- GSM7083770 H2O2_2 H2O2
- GSM7083771 H2O2_3 H2O2
- GSM7083772 heatshock1 heatshock
- GSM7083773 heatshock2 heatshock
- GSM7083774 heatshock3 heatshock
- GSM7083775 media1 media
- GSM7083776 media2 media
- GSM7083777 media3 media
- GSM7083778 DMSO1 DMSO
- GSM7083779 DMSO2 DMSO
- GSM7083780 DMSO3 DMSO
- GSM7083781 FG4592_1 FG4592
- GSM7083782 FG4592_2 FG4592
- GSM7083783 FG4592_3 FG4592
- GSE226784 YTHDF1 mitigates acute kidney injury via safeguarding m6A-methylated mRNAs in stress granules of renal tubules [MeRIP] 12 samples shares ythdf1, m6a-methylated, safeguarding, mitigates, granules, tubules, kidney, injury
- GSE226786 YTHDF1 mitigates acute kidney injury via safeguarding m6A-methylated mRNAs in stress granules of renal tubules [RNA-Seq] 15 samples shares ythdf1, m6a-methylated, safeguarding, mitigates, granules, tubules, kidney, injury
- GSE226785 YTHDF1 mitigates acute kidney injury via safeguarding m6A-methylated mRNAs in stress granules of renal tubules [RIP-Seq] 2 samples shares ythdf1, m6a-methylated, safeguarding, mitigates, granules, tubules, kidney, injury
- GSE315877 Metabolic surgery mitigates early kidney injury in obese youth with diabetes by suppressing mTORC1/JAK–STAT signaling 16 samples shares mitigates, kidney, injury
- GSE259432 KCNJ2 inhibition mitigates mechanical injury in human brain organoids 6 samples shares mitigates, injury
- GSE260532 KCNJ2 inhibition mitigates mechanical injury in human brain organoids [scRNA-seq] 2 samples shares mitigates, injury
- GSE319911 YTHDF1 functions as a non-canonical nuclear checkpoint that couples R-loop homeostasis to innate immune restraint and adaptive immune resistance in cancer（CUT&Tag） 18 samples shares ythdf1
- GSE319703 YTHDF1 functions as a non-canonical nuclear checkpoint that couples R-loop homeostasis to innate immune restraint and adaptive immune resistance in cancer（RNA-seq II） 12 samples shares ythdf1
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.