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Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance.[ATAC-seq]

GSE226912 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 4 samples Submitted 2024/09/24 Platform GPL24247
Summary
Here we identify a novel RAS-responsive element binding protein 1 short isoform, RREB1S, as a key in governing mitochondrial complex II translation to promote stemness and drug resistance of cancer stem cells of acute myeloid leukemia
Published in
Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance
Han G, Cui M, Lu P et al. · Cell stem cell 2024 · PMID 39357516 · doi:10.1016/j.stem.2024.09.008
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Also filed as BioProject PRJNA942248 and SRA study SRP426218. Searching any of these in the dataset finder brings you back here.

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