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Genome-wide chromatin binding of ERRα and ERRγ in SH-SY5Y cells

GSE227296 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2024/08/20 Platform GPL28038
Summary
The SH-SY5Y Human neuroblastoma cell line was subcloned from the SK-N-SH cell line, which has been isolated from a bone marrow biopsy of a 4 year-old female patient. To examine the transcriptional regulation by ERRα and ERRγ in human neuronal cells, we investigated chromatin binding regions of ERRαlpha and ERRγ genome-wide in the SH-SY5Y cells. We detected thier target genes, which were largely overlap.
Published in
ERRα and ERRγ coordinate expression of genes associated with Alzheimer's disease, inhibiting DKK1 to suppress tau phosphorylation
Sato K, Takayama KI, Saito Y et al. · Proceedings of the National Academy of Sciences of the United States of America 2024 · PMID 39231208 · doi:10.1073/pnas.2406854121
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Also filed as BioProject PRJNA941935 and SRA study SRP425944. Searching any of these in the dataset finder brings you back here.

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