Next generation sequencing of white adipose tissues from adipose FoxO1 knockout mice
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 24 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathwayRedox biology · 2023
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE227591_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA945879 and SRA study SRP427895. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 24 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7103620 gWAT-1, control
- GSM7103621 gWAT-2, control
- GSM7103622 iWAT-1, control
- GSM7103623 iWAT-2, control
- GSM7103624 gWAT-3, control
- GSM7103625 gWAT-4, control
- GSM7103626 iWAT-3, control
- GSM7103627 iWAT-4, control
- GSM7103628 gWAT-5, control
- GSM7103629 gWAT-6, control
- GSM7103630 iWAT-5, control
- GSM7103631 iWAT-6, control
- GSM7103632 gWAT-1, KO
- GSM7103633 gWAT-2, KO
- GSM7103634 iWAT-1, KO
- GSM7103635 iWAT-2, KO
- GSM7103636 gWAT-3, KO
- GSM7103637 gWAT-4, KO
- GSM7103638 iWAT-3, KO
- GSM7103639 iWAT-4, KO
- GSM7103640 gWAT-5, KO
- GSM7103641 gWAT-6, KO
- GSM7103642 iWAT-5, KO
- GSM7103643 iWAT-6, KO
- GSE253735 Loss of skeletal muscle Bmal1 +/- Exercise Training [Mouse liver, heart, inguinal white adipose and lung tissues 64 samples shares adipose, white
- GSE279927 RNA next-generation sequencing of cardiac fibroblasts isolated from young and old mice 7 days post-MI 25 samples shares generation, next
- GSE254258 BBSome-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue (scRNA-Seq) 10 samples shares adipose, white
- GSE281685 Transcription factor occupancy is affected by genetic variation in the white adipose tissue of C57BL6/j and 129S1/SvImJ mice [ChIP-seq] 16 samples shares adipose, white
- GSE282595 Concerted Actions of FoxO1 and Pparα in hepatic gene expression and metabolic adaptation 24 samples shares foxo1
- GSE267727 Transcriptome profiling of non-islet metabolic tissues in ~500 DO mouse liver, adipose, heart, and skeletal muscle tissue from mice fed high-fat, high-sugar diet [heart] 482 samples shares adipose
- GSE278003 Single cell RNA sequencing of CD45+ immune cells from tumor and tumor-adjacent mammary adipose tissue in a postmenopausal breast cancer model of lean, obese, and weight loss Trem2+/+ and Trem2-/- mice 92 samples shares adipose
- GSE267938 Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement 256 samples shares generation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.