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Effect of Kdm4a knockdown (KD) on gene expression in mosue PTR NEPC cells derived from Pb-Cre+,Pten f/f, Trp53 f/f, Rb1 f/f NEPC mouse model

GSE227717 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/01/21 Platform GPL21626
Summary
To investigate the role of KDM4A in the regulation of gene expression in NEPC cells, we established Kdm4a KD cell lines in which Kdm4a gene has been knocked down by shRNA. We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cells at two time points.
Published in
KDM4A promotes NEPC progression through regulation of MYC expression
Mak CSL, Zhu M, Fu J et al. · Cancer letters 2026 · PMID 41319861 · doi:10.1016/j.canlet.2025.218184
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Also filed as BioProject PRJNA946710 and SRA study SRP428295. Searching any of these in the dataset finder brings you back here.

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