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Single cell analysis of epithelial (EPI), immune (IMM) and stromal cells (double negative, DN) cells from murine small intestine in steady state following LXR activation.

GSE227726 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/07/19 Platform GPL24247
Summary
LXRs (LXRa and LXRb) are widely expresded in a variety of cell types. We addressed how transient LXR activation using GW3965 impacts the cellular composition and/or transcriptional changes in the SI of WT mice.
Published in
Liver X receptor unlinks intestinal regeneration and tumorigenesis
Das S, Parigi SM, Luo X et al. · Nature 2025 · PMID 39567700 · doi:10.1038/s41586-024-08247-6
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Also filed as BioProject PRJNA946717 and SRA study SRP428255. Searching any of these in the dataset finder brings you back here.

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