Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide

• GSE294955 ZFTA–RELA ependymomas make itaconate to epigenetically drive fusion expression [ChIP-Seq] 18 samples
• GSE266386 Suppressing Aberrant Hedgehog Pathway and Overcoming Resistance to Smoothened Antagonists via Targeting Super-enhancer-driven Transcriptional Dependencies [ChIP-seq] 14 samples
• GSE261742 Identification of epigenetic regulators of fibrotic transformation in cardiac fibroblasts through bulk and single-cell CRISPR screens 69 samples
• GSE303627 MYST acetyltransferases are a targetable therapeutic vulnerability in SETBP1-mutant leukemia [CUT&Run] 46 samples
• GSE341319 Vitamin B2 Sensing by the Nuclear Receptor AhR Reprograms Hepatic Metabolism [ATAC-Seq] 20 samples
• GSE132266 scChIC-seq reveals focusing of global chromatin domains during differentiation 80 samples
• GSE240230 CUT&TAG analysis of R-loops in Mcm8 knockout MEFs and CUT&TAG analysis of R-loops and MCM8-binding site in HEK293 cells 6 samples
• GSE294966 ChIP-seq for beta-catenin, EZH2, EED, KMT2B, H3K4me3, H3K27me3 and sequential chipseq 148 samples

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