RSK1 is an exploitable dependency in myeloid malignancies [scRNA-seq]
Single-cell RNA-seq · human · 2 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Homo sapiens (human)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemiaNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE228759_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA951431 and SRA study SRP430506. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE283710 RSK1 is an exploitable dependency in myeloid malignancies [CD34RNAseq] 90 samples shares rsk1, malignancies, exploitable, dependency, myeloid
- GSE283711 RSK1 is an exploitable dependency in myeloid malignancies [CD14_RNAseq] 68 samples shares rsk1, malignancies, exploitable, dependency, myeloid
- GSE228758 RSK1 is an exploitable dependency in myeloid malignancies [RNA-seq] 16 samples shares rsk1, malignancies, exploitable, dependency, myeloid
- GSE228760 RSK1 is an exploitable dependency in myeloid malignancies. 191 samples shares rsk1, malignancies, exploitable, dependency, myeloid
- GSE229174 RSK1 is an exploitable dependency in myeloid malignancies [CUT&Tag] 9 samples shares rsk1, malignancies, exploitable, dependency, myeloid
- GSE229220 RSK1 is an exploitable dependency in myeloid malignancies [ATAC-seq] 6 samples shares rsk1, malignancies, exploitable, dependency, myeloid
- GSE213002 ATR/CHK1/WEE1 dependency in SRSF2-mutated myeloid malignancies 16 samples shares malignancies, dependency, myeloid
- GSE281161 A phase 1 study of the CDK9 inhibitor voruciclib in relapsed/refractory acute myeloid leukemia and B-cell malignancies 31 samples shares malignancies, myeloid
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.