COVID-19 vaccination is associated with attenuation of inflammatory responses during breakthrough disease
Non-coding RNA profiling · human · 399 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 399 samples: 399 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Multi-omics analysis reveals COVID-19 vaccine induced attenuation of inflammatory responses during breakthrough diseaseNature communications · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE228842_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA951713 and SRA study SRP430644. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 399 sample titles: 399 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7139920 WTCHG_72175193_D0_ChAdOx1_+ve
- GSM7139921 WTCHG_72185194_CT_ChAdOx1_+ve
- GSM7139922 WTCHG_72195195_CT+7_ChAdOx1_+ve
- GSM7139923 WTCHG_72205196_D0_MenACWY_+ve
- GSM7139924 WTCHG_72215197_CT_MenACWY_+ve
- GSM7139925 WTCHG_72225198_CT+7_MenACWY_+ve
- GSM7139926 WTCHG_72235199_D0_ChAdOx1_-ve
- GSM7139927 WTCHG_72245200_CT_ChAdOx1_-ve
- GSM7139928 WTCHG_72255201_CT+7_ChAdOx1_-ve
- GSM7139929 WTCHG_72265202_D0_MenACWY_-ve
- GSM7139930 WTCHG_72275203_CT_MenACWY_-ve
- GSM7139931 WTCHG_72285204_D0_MenACWY_-ve
- GSM7139932 WTCHG_72295205_CT_MenACWY_-ve
- GSM7139933 WTCHG_72305206_CT_ChAdOx1_-ve
- GSM7139934 WTCHG_72315207_CT+7_ChAdOx1_-ve
- GSM7139935 WTCHG_72325208_D0_MenACWY_-ve
- GSM7139936 WTCHG_72335209_CT_MenACWY_-ve
- GSM7139937 WTCHG_72345210_CT+7_MenACWY_-ve
- GSM7139938 WTCHG_72355211_D0_ChAdOx1_+ve
- GSM7139939 WTCHG_72365212_CT_ChAdOx1_+ve
- GSM7139940 WTCHG_72375213_CT+7_ChAdOx1_+ve
- GSM7139941 WTCHG_72385214_D0_MenACWY_-ve
- GSM7139942 WTCHG_72395215_CT_MenACWY_-ve
- GSM7139943 WTCHG_72405216_CT_MenACWY_-ve
- GSM7139944 WTCHG_72415217_CT_ChAdOx1_-ve
- GSM7139945 WTCHG_72425218_D0_ChAdOx1_-ve
- GSM7139946 WTCHG_72435219_CT_ChAdOx1_-ve
- GSM7139947 WTCHG_72445220_CT+7_ChAdOx1_-ve
- GSM7139948 WTCHG_72455221_D0_ChAdOx1_-ve
- GSM7139949 WTCHG_72465222_CT_ChAdOx1_-ve
- GSM7139950 WTCHG_72475223_CT+7_ChAdOx1_-ve
- GSM7139951 WTCHG_72485224_CT_ChAdOx1_+ve
- GSM7139952 WTCHG_72495225_CT_ChAdOx1_+ve
- GSM7139953 WTCHG_72505226_CT+7_ChAdOx1_+ve
- GSM7139954 WTCHG_72515227_CT_ChAdOx1_+ve
- GSM7139955 WTCHG_72525228_CT+7_ChAdOx1_+ve
- GSM7139956 WTCHG_72535229_CT_MenACWY_-ve
- GSM7139957 WTCHG_72545230_CT_MenACWY_-ve
- GSM7139958 WTCHG_72555231_CT+7_MenACWY_-ve
- GSM7139959 WTCHG_72565232_CT_MenACWY_-ve
+ 359 more — browse all 399 samples with per-sample file links →
- GSE261862 Prior vaccination prevents overactivation of innate immune responses during COVID-19 breakthrough infection 16 samples shares covid-19, breakthrough, vaccination
- GSE281864 Detailed delineation of the immune response to COVID-19 mRNA vaccination via high-temporal frequency blood transcriptomics [third] 193 samples shares covid-19, vaccination
- GSE243219 Comparative Analysis of Host Responses Between Sepsis and COVID-19: A Prospective Observational Study of Whole Blood Transcriptome 144 samples shares covid-19
- GSE283746 Comparative Single-Cell Analyses in Infants Revealed RSV-Specific Declines in NK Cell Responses and COVID-19-Specific Increases in Inflammatory Responses [COVID_RSV_scRNA] 68 samples shares covid-19
- GSE300696 Identification of reactive CpGs and RNA expression in early COVID-19 through cis-eQTM analysis reflecting disease severity and recovery [RNA-seq] 346 samples shares covid-19
- GSE210435 TET2 Mutant Clonal Hematopoiesis Enhances Severity of COVID-19 Related Cytokine Release Syndrome and is Associated with Increased Mortality. 363 samples shares covid-19
- GSE297329 Evolution of SARS-CoV-2 T cell responses as a function of multiple COVID-19 boosters 98 samples shares covid-19
- GSE243217 Comparative Analysis of Host Responses Between Sepsis and COVID-19: A Prospective Observational Study of Whole Blood Transcriptome (RNA-Seq) 72 samples shares covid-19
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.