Molecular and immune profiles linked to androgen response categories in metastatic castration-resistant prostate cancers (mCRPC)
RNA-seq (gene expression) · human · 56 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Prostate cancerThis series is part of our curated briefing on it.
- Samples
- 56 samples: 56 × Prostate Cancer PatientGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A Modular Trial of Androgen Signaling Inhibitor Combinations Testing a Risk-Adapted Strategy in Patients with Metastatic Castration-Resistant Prostate CancerClinical cancer research : an official journal of the American Association for Cancer Research · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE229394_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA954354 and SRA study SRP432019. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 56 samples.
How we read this: 1 replicated groups read from 56 sample titles; they account for 56 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7162719 Prostate Cancer Patient 1 Prostate Cancer Patient
- GSM7162720 Prostate Cancer Patient 2 Prostate Cancer Patient
- GSM7162721 Prostate Cancer Patient 3 Prostate Cancer Patient
- GSM7162722 Prostate Cancer Patient 4 Prostate Cancer Patient
- GSM7162723 Prostate Cancer Patient 5 Prostate Cancer Patient
- GSM7162724 Prostate Cancer Patient 6 Prostate Cancer Patient
- GSM7162725 Prostate Cancer Patient 7 Prostate Cancer Patient
- GSM7162726 Prostate Cancer Patient 8 Prostate Cancer Patient
- GSM7162727 Prostate Cancer Patient 9 Prostate Cancer Patient
- GSM7162728 Prostate Cancer Patient 10 Prostate Cancer Patient
- GSM7162729 Prostate Cancer Patient 11 Prostate Cancer Patient
- GSM7162730 Prostate Cancer Patient 12 Prostate Cancer Patient
- GSM7162731 Prostate Cancer Patient 13 Prostate Cancer Patient
- GSM7162732 Prostate Cancer Patient 14 Prostate Cancer Patient
- GSM7162733 Prostate Cancer Patient 15 Prostate Cancer Patient
- GSM7162734 Prostate Cancer Patient 16 Prostate Cancer Patient
- GSM7162735 Prostate Cancer Patient 17 Prostate Cancer Patient
- GSM7162736 Prostate Cancer Patient 18 Prostate Cancer Patient
- GSM7162737 Prostate Cancer Patient 19 Prostate Cancer Patient
- GSM7162738 Prostate Cancer Patient 20 Prostate Cancer Patient
- GSM7162739 Prostate Cancer Patient 21 Prostate Cancer Patient
- GSM7162740 Prostate Cancer Patient 22 Prostate Cancer Patient
- GSM7162741 Prostate Cancer Patient 23 Prostate Cancer Patient
- GSM7162742 Prostate Cancer Patient 24 Prostate Cancer Patient
- GSM7162743 Prostate Cancer Patient 25 Prostate Cancer Patient
- GSM7162744 Prostate Cancer Patient 26 Prostate Cancer Patient
- GSM7162745 Prostate Cancer Patient 27 Prostate Cancer Patient
- GSM7162746 Prostate Cancer Patient 28 Prostate Cancer Patient
- GSM7162747 Prostate Cancer Patient 29 Prostate Cancer Patient
- GSM7162748 Prostate Cancer Patient 30 Prostate Cancer Patient
- GSM7162749 Prostate Cancer Patient 31 Prostate Cancer Patient
- GSM7162750 Prostate Cancer Patient 32 Prostate Cancer Patient
- GSM7162751 Prostate Cancer Patient 33 Prostate Cancer Patient
- GSM7162752 Prostate Cancer Patient 34 Prostate Cancer Patient
- GSM7162753 Prostate Cancer Patient 35 Prostate Cancer Patient
- GSM7162754 Prostate Cancer Patient 36 Prostate Cancer Patient
- GSM7162755 Prostate Cancer Patient 37 Prostate Cancer Patient
- GSM7162756 Prostate Cancer Patient 38 Prostate Cancer Patient
- GSM7162757 Prostate Cancer Patient 39 Prostate Cancer Patient
- GSM7162758 Prostate Cancer Patient 40 Prostate Cancer Patient
+ 16 more — browse all 56 samples with per-sample file links →
- GSE115501 RNA sequencing on circulating tumor cells from prostate cancer patients 136 samples same disease briefing · shares prostate
- GSE222467 The RNA binding proteins LARP4A and LARP4B promote tumour growth and metastasis in prostate cancer and osteosarcoma 12 samples same disease briefing · shares prostate
- GSE300947 A novel six-biomarker panel identified from male breast cancer-associated fibroblasts demonstrates prognostic power for prostate tumors 6 samples same disease briefing · shares prostate
- GSE71008 Plasma extracellular RNA profiles in healthy and cancer patients 192 samples same disease briefing · shares profiles
- GSE120181 Human prostate cancer cell line, 22Rv1: Control vs. luteolin treatment 2 samples same disease briefing · shares prostate
- GSE242541 ONECUT2 is a druggable driver of luminal to basal breast cancer plasticity 12 samples same disease briefing
- GSE297652 Single-cell transcriptomic profiles of metastatic lesion biopsies and PBMCs from M1-stage prostate cancer patients 12 samples shares metastatic, profiles, prostate
- GSE252902 Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer 130 samples shares castration-resistant, androgen, prostate
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.