Translational application of pharmacogenomics for refractory lung cancer II
RNA-seq (gene expression) · human · 99 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Lung cancerThis series is part of our curated briefing on it.
- Samples
- 99 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- VEGF Signal Complexity Confers Resistance to Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel in EGFR-Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung CancerMedComm · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE229535_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA954840 and SRA study SRP432320. Searching any of these in the dataset finder brings you back here.
The grouping that defines any comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Sample titles run NCCLu-099 … NCCLu-475 and carry no group information.
- GSM7165007 NCCLu-099
- GSM7165008 NCCLu-145
- GSM7165009 NCCLu-162
- GSM7165010 NCCLu-191
- GSM7165011 NCCLu-196
- GSM7165012 NCCLu-200
- GSM7165013 NCCLu-206
- GSM7165014 NCCLu-207
- GSM7165015 NCCLu-212
- GSM7165016 NCCLu-213
- GSM7165017 NCCLu-214
- GSM7165018 NCCLu-231
- GSM7165019 NCCLu-237
- GSM7165020 NCCLu-238
- GSM7165021 NCCLu-250
- GSM7165022 NCCLu-257
- GSM7165023 NCCLu-261
- GSM7165024 NCCLu-277
- GSM7165025 NCCLu-285
- GSM7165026 NCCLu-287
- GSM7165027 NCCLu-292
- GSM7165028 NCCLu-295
- GSM7165029 NCCLu-296
- GSM7165030 NCCLu-298
- GSM7165031 NCCLu-299
- GSM7165032 NCCLu-301
- GSM7165033 NCCLu-303
- GSM7165034 NCCLu-304
- GSM7165035 NCCLu-306
- GSM7165036 NCCLu-308
- GSM7165037 NCCLu-311
- GSM7165038 NCCLu-313
- GSM7165039 NCCLu-316
- GSM7165040 NCCLu-317
- GSM7165041 NCCLu-318
- GSM7165042 NCCLu-320
- GSM7165043 NCCLu-324
- GSM7165044 NCCLu-326
- GSM7165045 NCCLu-327
- GSM7165046 NCCLu-328
+ 59 more — browse all 99 samples with per-sample file links →
- GSE127465 Single cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species 40 samples same disease briefing · shares lung
- GSE103550 Lung Cancer Cell-Mediated Skeletal Muscle Mitochondrial Dysfunction is Mitigated by 1a,25-Dihydroxyvitamin D3 24 samples same disease briefing · shares lung
- GSE241518 High-throughout sequencing of colorectal cancer and non-small cell lung cancer cells treated actived compound YHM18 4 samples same disease briefing · shares lung
- GSE114761 Transforming Growth Factor β-Induced Epithelial-to-Mesenchymal Signature Predicts Metastasis-Free Survival in Non-Small Cell Lung Cancer. 42 samples same disease briefing · shares lung
- GSE10072 Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival 107 samples same disease briefing · shares lung
- GSE17958 Affymetrix SNP array data for 47 lung squamous cell carcinoma and 40 esophageal squamous cell carcinoma samples. 87 samples same disease briefing · shares lung
- GSE104244 Bone Marrow Derived Macrophages, NSCLC cell lines, and Kras G12D Lung Tumors Treated with Epigenetic Agents 33 samples same disease briefing · shares lung
- GSE117570 Reprogramming of Tumor-infiltrating Immune Cells in Early Stage of NSCLC 8 samples same disease briefing
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.