← BioTransfer GEO Dataset Finder
GEO series

Transcriptomic changes induced by knocking down EPIC1 in cancer cell lines [RNA-seq II]

GSE229722 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/06/10 Platform GPL18573
Summary
To investigate and determine the function of EPIC1 in cancer cells, we knockdown EPIC1 in Hs578T, A2780, and A2780cis cells using siRNA.
Published in
The lncRNA EPIC1 suppresses dsRNA-induced type I IFN signaling and is a therapeutic target to enhance TNBC response to PD-1 inhibition
Pattarayan D, Wang Y, Wang Z et al. · Science signaling 2025 · PMID 40794843 · doi:10.1126/scisignal.adr9131
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE229722_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA955705 and SRA study SRP432704. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 9 more — browse all 9 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.