← BioTransfer GEO Dataset Finder
GEO series

Microglia response upon demyelinating injury [ATAC-seq]

GSE230187 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 4 samples Submitted 2024/07/24 Platform GPL18480
Summary
To understand the impaired transcriptional regulation of microglia/macropahges in aging following demyelinating injury. Transcriptional regulation requires the repositioning of the nucleosomes around promoters and enhancers, thereby making chromatin accessible to transcription factors.
Published in
Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
Tiwari V, Prajapati B, Asare Y et al. · Immunity 2024 · PMID 39053462 · doi:10.1016/j.immuni.2024.07.001
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE230187_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA957805 and SRA study SRP433600. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 4 more — browse all 4 samples with per-sample file links →

Similar datasets

Search all mouse ChIP / ATAC / CUT&Tag datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.