GEO series
GATAD2B containing NuRD complex drives R-loop dependent chromatin boundary formation at double strand breaks
GSE230710
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing
18 samples
2024/04/17
GPL24676
Summary
To understand how components of NuRD could be recruited to DNA double-stranded break sites, we generate site-specific DNA double strand breaks through an inducible endonuclease AsiSI-ER system by adding 4-OHT, we applied antibodies against GATAD2B and HDAC1, both of which are components of NuRD complex, to pero ChIP in either DMSO or 4OHT treatment condition.
Download
NCBI GEO page ↗
Paper (PMID 38719994) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
human ChIP / ATAC / CUT&Tag datasets →
Similar datasets
- GSE316079 SLF2 and SMC5 dysfunction drives HSC aging and predisposes to MDS, defining a new inherited bone marrow failure syndrome [ATAC-seq] 6 samples
- GSE334112 Reversible epiblast regionalisation determines differentiation potential of human PSCs [ATAC-seq] 38 samples
- GSE327821 Single-molecule, single-cell profiling of linked chromatin states [Single_cell_CoCUT&Tag] 200 samples
- GSE329512 SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry 19 samples
- GSE318107 CAD-C: An engineered nuclease enables repair-free in situ proximity ligation and nucleosome-resolution chromosome walks in human cells [Cut & Tag] 10 samples
- GSE142751 Genome-wide maps of chromatin state in 142 cancer cell lines [cell line] 855 samples
- GSE338521 Somatic mutations reveal the ontogeny of microglia in human aging 36 samples
- GSE323981 MEF2C controls lysosomal and lipid clearance programs linked to Alzheimer’s disease risk in macrophages [ATAC-seq] 8 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.