GEO series
Macrophage containing multicellular lung organoids [bulkRNA-seq]
GSE231466
Homo sapiens
Expression profiling by high throughput sequencing
10 samples
2024/07/07
GPL24676GPL16791
Summary
Proper lung development and function maintenance depend on the cross-talk between resident immune cell populations and lung epithelial cells. However, understanding the underlying cellular and molecular mechanisms are difficult to study in human. Here, we present a method to develop macrophage-containing alveolar organoids from human pluripotent stem cells to investigate reciprocal interactions between alveolar macrophages and epithelial cells in lung development.
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Paper (PMID 40199883) ↗
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