Impact of azide metabolic glycoengineering and bioorthogonal click chemistry cell-cell tethering in adipose tissue-derived mesenchymal stromal cells
RNA-seq (gene expression) · human · 15 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 15 samples: 5 × 2D_Native vs 5 × 2D_Glycoengineered vs 5 × 3D_Day 1Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE231507_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA949992 and SRA study SRP429954. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 15 samples.
How we read this: 3 replicated groups read from 15 sample titles; they account for 15 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7286937 2D_Native_1 2D_Native
- GSM7286938 2D_Native_2 2D_Native
- GSM7286939 2D_Native_3 2D_Native
- GSM7286940 2D_Native_4 2D_Native
- GSM7286941 2D_Native_5 2D_Native
- GSM7286942 2D_Glycoengineered_1 2D_Glycoengineered
- GSM7286943 2D_Glycoengineered_2 2D_Glycoengineered
- GSM7286944 2D_Glycoengineered_3 2D_Glycoengineered
- GSM7286945 2D_Glycoengineered_4 2D_Glycoengineered
- GSM7286946 2D_Glycoengineered_5 2D_Glycoengineered
- GSM7286947 3D_Day 1_1 3D_Day 1
- GSM7286948 3D_Day 1_2 3D_Day 1
- GSM7286949 3D_Day 1_3 3D_Day 1
- GSM7286950 3D_Day 1_4 3D_Day 1
- GSM7286951 3D_Day 1_5 3D_Day 1
- GSE314750 Increased arrhythmic risk in obesity is transduced by adipose tissue-derived extracellular vesicles 30 samples shares tissue-derived, adipose
- GSE316735 Directed Evolution of Enzymes for Bioorthogonal Chemistry Using Acid Chloride Proximity Labeling 16 samples shares bioorthogonal, chemistry
- GSE319722 Spatial dynamics links PD-L1 and Tumor-Associated Macrophage–Enriched Niches to Immune and Mesenchymal States in microsatellite stable colorectal cancer 117 samples shares mesenchymal
- GSE273244 BMP4 induces a p21-dependent cell state shift in glioblastoma linking mesenchymal transition to senescence 80 samples shares mesenchymal
- GSE316614 Targeting mutation-agnostic disease pathways ameliorates ciliopathy-related mesenchymal drift in RPE 69 samples shares mesenchymal
- GSE251756 Cell and state-specific eQTL analysis in human endometrial mesenchymal cells uncovers candidate susceptibility genes for reproductive diseases and traits 59 samples shares mesenchymal
- GSE256064 Proneural-Mesenchymal hybrid glioblastoma cells are resistant to therapy and dependent on nuclear import-bulk RNAseq 56 samples shares mesenchymal
- GSE247652 To understand the transcriptional changes in human HSPCs induced upon co-culture with OP9M2 Mesenchymal Stromal Cells and their conditioned medium. 48 samples shares mesenchymal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.