In vitro reconstitution of epigenetic reprogramming in the human germ line
DNA methylation · human · 119 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Samples
- 119 samples: 112 distinct titles, 5 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- In vitro reconstitution of epigenetic reprogramming in the human germ lineNature · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE232078_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA970753 and SRA study SRP436186. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 119 sample titles: 112 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7304281 585B1 BTAG WT
- GSM7304282 585B1 BTAG TET1 KO#1
- GSM7304283 585B1 BTAG TET1 KO#2
- GSM7304284 NCLCN AGVT c11
- GSM7304285 NCLCN AGVT c56
- GSM7304286 NCLCN AGVT c86
- GSM7304287 NCLCN AGVT c117
- GSM7304288 M1-AGDT c32_1 AG no BMP2
- GSM7304289 M1-AGDT c32_2 AG no BMP2
- GSM7304290 M1-AGDT c32 AG
- GSM7304291 M1-AGDT c82_1 AG
- GSM7304292 M1-AGDT c82_2 AG
- GSM7304293 M1-AGDT c82 AGDT
- GSM7304294 M1-AGDT c122 AGDT
- GSM7304295 F1-AGVT iPSC
- GSM7304296 F1-AGVT hPGCLC_1
- GSM7304297 F1-AGVT hPGCLC_2
- GSM7304298 F1-AGVT c72AG
- GSM7304299 F1-AGVT c72AGVT
- GSM7304300 F1-AGVT c86AGVT
- GSM7304301 F1-AGVT c127AGVT
- GSM7304302 M1-BTAG c12 TET1 WT
- GSM7304303 TET1KO c12KO1
- GSM7304304 TET1KO c12KO2
- GSM7304305 M1-BTAG c42 TET1 WT
- GSM7304306 TET1KO c42KO1
- GSM7304307 TET1KO c42KO2
- GSM7311485 F1-AGVT_iPSC (MS356_047)
- GSM7311486 F1-AGVT_hPGCLC,rep1 (MS356_048)
- GSM7311487 F1-AGVT_hPGCLC,rep2 (MS356_059)
- GSM7311488 F1-AGVT_c11_AG (MS356_045)
- GSM7311489 F1-AGVT_c12_AG (MS356_060)
- GSM7311490 F1-AGVT_c21_AG (MS356_046)
- GSM7311491 F1-AGVT_c24_AG (MS356_061)
- GSM7311492 F1-AGVT_c35_AG (MS356_062)
- GSM7311493 F1-AGVT_c44_AG (MS356_049)
- GSM7311494 F1-AGVT_c45_AG (MS356_063)
- GSM7311495 F1-AGVT_c65_AG (MS356_051)
- GSM7311496 F1-AGVT_c86_AG (MS356_053)
- GSM7311497 F1-AGVT_c67_AGVT (MS356_065)
+ 79 more — browse all 119 samples with per-sample file links →
- GSE232076 In vitro reconstitution of epigenetic reprogramming in the human germ line [RNA-Seq] 89 samples shares reconstitution, reprogramming, epigenetic, vitro, germ, line
- GSE278576 Epigenetic and 3D genome reprogramming during the aging of human hippocampus 80 samples shares reprogramming, epigenetic
- GSE307670 Epigenetic reprogramming of stromal cell states underpins pathologic tissue niches in Crohn’s disease 148 samples shares reprogramming, epigenetic
- GSE339365 Genome-wide H3K4me3 profiling of circulating immune cells reveals dynamic epigenetic reprogramming during acute critical COVID-19 120 samples shares reprogramming, epigenetic
- GSE283621 Single-cell multi-omics analysis identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma 79 samples shares reprogramming, epigenetic
- GSE324208 Epigenetic reprogramming drives cellular and phenotypic plasticity in liposarcoma 42 samples shares reprogramming, epigenetic
- GSE283619 Single-cell multi-omics analysis identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma [Multiome] 30 samples shares reprogramming, epigenetic
- GSE308983 Reprogramming lineage features promotes epithelial behavior in carcinoma cells [ChIP-Seq] 23 samples shares reprogramming, line
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.