Targeting the Epigenome Reduces Keloid Fibroblast Cell Proliferation, Migration and Invasion
RNA-seq (gene expression) · human · 28 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 28 samples: 22 distinct titles, 6 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Targeting the Epigenome Reduces Keloid Fibroblast Cell Proliferation, Migration, and InvasionThe Journal of investigative dermatology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE232079_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA970758 and SRA study SRP436687. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 28 sample titles: 22 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7311577 PCS-201-021 P5 DMSO 1
- GSM7311578 PCS-201-021 P5 corin 1
- GSM7311579 PCS-201-021 P4 DMSO 2
- GSM7311580 PCS-201-021 P4 corin 2
- GSM7311581 CRL-1762 P4 DMSO 1
- GSM7311582 CRL-1762 P4 corin 1
- GSM7311583 CRL-1762 P4 DMSO 2
- GSM7311584 CRL-1762 P4 corin 2
- GSM7311585 PK1 P7 DMSO 1
- GSM7311586 PK1 P7 corin 1
- GSM7311587 PK1 P7 DMSO 2
- GSM7311588 PK1 P7 corin 2
- GSM7311589 PK2 P8 DMSO 1
- GSM7311590 PK2 P8 corin 1
- GSM7311591 PK2 P4 DMSO 2
- GSM7311592 PK2 P4 corin 2
- GSM7311593 PK3 P3 DMSO 1
- GSM7311594 PK3 P3 corin 1
- GSM7311595 PK3 P4 DMSO 2
- GSM7311596 PK3 P4 corin 2
- GSM7311597 PK4 P2 DMSO 1
- GSM7311598 PK4 P2 corin 1
- GSM7311599 PK4 P2 DMSO 2
- GSM7311600 PK4 P2 corin 2
- GSM7311601 PNF4 P3 DMSO 1
- GSM7311602 PNF4 P3 corin 1
- GSM7311603 PNF4 P4 DMSO 2
- GSM7311604 PNF4 P4 corin 2
- GSE278112 Regulation of pancreatic cancer migration by signal convergence in the epigenome [RNA-Seq] 36 samples shares epigenome, migration
- GSE303591 Single-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features [bulk-RNAseq] 16 samples shares fibroblast, keloid
- GSE217494 Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis I 44 samples shares fibroblast, targeting
- GSE218391 Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis II 21 samples shares fibroblast, targeting
- GSE281471 Targeting CD206+ macrophages disrupts the establishment of a key anti-tumor immune axis [Bulk RNA-seq] 243 samples shares targeting
- GSE275647 Role of Cancer-Associated Fibroblasts in Prognostic Stratification of Advanced-Stage Gastric Cancer through Interacting with Endothelial and Malignant Epithelial Cells [AGC RNA-seq] 216 samples shares fibroblast
- GSE222556 Neoadjuvant PARPi or Chemotherapy in Ovarian Cancer Informs Targeting Effector Treg Cells for Homologous-Recombination-Deficient Tumors [10x scRNA-seq] 67 samples shares targeting
- GSE284664 RESET: A reversible TCR-coupled antigen receptor with superior targeting sensitivity and pharmacologically controlled anti-tumor activity 62 samples shares targeting
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.