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Genome-wide studies identify genes regulated by co-activator BRD4 in APL cells [RNA-seq]

GSE232294 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2024/07/30 Platform GPL16791
Summary
Acute promyelocytic leukemia (APL) is characterized by a specific t(15;17) chromosome translocation that generates the promyelocytic leukemia/retinoic acid receptor-α (PML/RARα) fusion gene. However, the mechanism underlying PML/RARα mediated transcriptional dysregulation remain unclear. Here, we performed the transcription profiling of BRD4 in NB4, an APL patient-derived cell line.
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Direct links to NCBI, no account and no request form: the whole study as GSE232294_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA971554 and SRA study SRP437075. Searching any of these in the dataset finder brings you back here.

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