Exploring the Stability of Genomic Imprinting and X-Chromosome Inactivation in the Aged Brain
DNA methylation · mouse · 83 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Mus musculus (mouse)
- Samples
- 83 samples: 83 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE232548_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA972703 and SRA study SRP437727. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 83 sample titles: 83 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7350031 999hcp MOUSE 1
- GSM7350032 1000hcp MOUSE 2
- GSM7350033 1084hcp MOUSE 3
- GSM7350034 1086hcp MOUSE 4
- GSM7350035 734hcp MOUSE 11
- GSM7350036 1619hcp MOUSE 5
- GSM7350037 1622hcp MOUSE 6
- GSM7350038 1678hcp MOUSE 7
- GSM7350039 1679hcp MOUSE 8
- GSM7350040 23971hcp MOUSE 10
- GSM7350041 1681hcp MOUSE 9
- GSM7350042 1000_CB MOUSE 2 lane7651_ACTTGATG_1000_C
- GSM7350043 1000_HCP MOUSE 2 lane7651_CAGATCTG_1000_HC
- GSM7350044 1000_LUNG MOUSE 2 lane7651_CTTGTACT_1000_LUNG
- GSM7350045 1000_PFC MOUSE 2 lane7651_GATCAGCG_1000_PFC
- GSM7350046 1000_NA MOUSE 2 lane7651_GGCTACAG_1000_NA
- GSM7350047 1000_HY MOUSE 2 lane7651_TAGCTTGT_1000_HY
- GSM7350048 1000_CB MOUSE 2 lane7950_ACAGTGGT_1000_Cerb
- GSM7350049 1000_LUNG MOUSE 2 lane7950_GCCAATGT_1000_Lung
- GSM7350050 1000_HCP MOUSE 2 lane7950_TGACCACT_1000_HCP
- GSM7350051 1084_PFC MOUSE 3 lane7651_TAAGCGTT_1084_PFC
- GSM7350052 1084_HY MOUSE 3 lane7651_TCCGTCTT_1084_HY
- GSM7350053 1084_CB MOUSE 3 lane7651_TCTCGGTT_1084_C
- GSM7350054 1084_HCP MOUSE 3 lane7651_TGGTTGTT_1084_HC
- GSM7350055 1084_NA MOUSE 3 lane7651_TGTACCTT_1084_NA
- GSM7350056 1084_LUNG MOUSE 3 lane7651_TTCTGTGT_1084_LUNG
- GSM7350057 1084_CB MOUSE 3 lane7950_ACTTGATG_1084_Cerb
- GSM7350058 1084_HCP MOUSE 3 lane7950_CAGATCTG_1084_HCP
- GSM7350059 1084_LUNG MOUSE 3 lane7950_GATCAGCG_1084_Lung
- GSM7350060 1086_PFC MOUSE 4 lane7651_TCGAGCGT_1086_PFC
- GSM7350061 1086_HCP MOUSE 4 lane7651_TCTGCTGT_1086_HCP
- GSM7350062 1086_HY MOUSE 4 lane7651_TGATACGT_1086_HY
- GSM7350063 1086_NA MOUSE 4 lane7651_TGCATAGT_1086_NA
- GSM7350064 1086_LUNG MOUSE 4 lane7651_TTGACTCT_1086_LUNG
- GSM7350065 1086_CB MOUSE 4 lane7651_TTGGAGGT_1086_C
- GSM7350066 1086_LUNG MOUSE 4 lane7950_CTTGTACT_1086_Lung
- GSM7350067 1086_CB MOUSE 4 lane7950_GGCTACAG_1086_Cerb
- GSM7350068 1086_HCP MOUSE 4 lane7950_TAGCTTGT_1086_HCP
- GSM7350069 1619_HY MOUSE 5 lane7651_TACAGGAT_1619_HY
- GSM7350070 1619_PFC MOUSE 5 lane7651_TAGTGACT_1619_PFC
+ 43 more — browse all 83 samples with per-sample file links →
- GSE232546 Exploring the Stability of Genomic Imprinting and X-Chromosome Inactivation in the Aged Brain (RNA-Seq) 11 samples shares x-chromosome, inactivation, imprinting, exploring, stability, brain, aged
- GSE251883 NFkB Signaling is Required for Xist RNA Localization at the Inactive X and for X-Chromosome Inactivation Maintenance Following T cell Activation 39 samples shares x-chromosome, inactivation
- GSE219083 G-quadruplex folding in Xist RNA antagonizes PRC2 activity for step-wise regulation of X-chromosome inactivation 36 samples shares x-chromosome, inactivation
- GSE295196 m6A RNA methylation in the maintenance of X-chromosome inactivation and X to autosome dosage compensation in early embryogenesis [RNA-Seq] 14 samples shares x-chromosome, inactivation
- GSE251879 NFkB Signaling is Required for Xist RNA Localization at the Inactive X and for X-Chromosome Inactivation Maintenance Following T cell Activation [CUT&RUN] 14 samples shares x-chromosome, inactivation
- GSE274784 Exploring the Biological Mechanisms of Severe COVID-19 in the Elderly: Insights from an Aged Mouse Model 13 samples shares exploring, aged
- GSE309424 SETDB1/HUSH modulates Xist RNA levels during establishment of X chromosome inactivation 292 samples shares inactivation
- GSE319319 Xist RNA Dependent and Independent Mechanisms Regulate Dynamic X Chromosome Inactivation in B Lymphocytes 202 samples shares inactivation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.