ISL1 and POU4F1 Directly Interact to Regulate the Differentiation and Survival of Inner Ear Sensory Neurons
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 20 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 7 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- ISL1 and POU4F1 Directly Interact to Regulate the Differentiation and Survival of Inner Ear Sensory NeuronsThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE233840_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA978073 and SRA study SRP440456. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 19 samples.
How we read this: 7 replicated groups read from 20 sample titles; they account for 19 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7437670 E11_5_CVG_ISL1_26_Rep1
- GSM7437671 E11_5_CVG_ISL1_70_Rep1 E11_5_CVG_ISL1_70
- GSM7437672 E11_5_CVG_ISL1_70_Rep2 E11_5_CVG_ISL1_70
- GSM7437673 E11_5_CVG_ISL1_70_Rep3 E11_5_CVG_ISL1_70
- GSM7437674 E11_5_CVG_POU4F1_Rep1 E11_5_CVG_POU4F1
- GSM7437675 E11_5_CVG_POU4F1_Rep2 E11_5_CVG_POU4F1
- GSM7437676 E11_5_CVG_IgGR_Rep1 E11_5_CVG_IgGR
- GSM7437677 E11_5_CVG_IgGR_Rep2 E11_5_CVG_IgGR
- GSM7437678 E11_5_CVG_IgGR_Rep3 E11_5_CVG_IgGR
- GSM7437679 E11_5_CVG_IgGM_Rep1 E11_5_CVG_IgGM
- GSM7437680 E11_5_CVG_IgGM_Rep2 E11_5_CVG_IgGM
- GSM7437681 E11_5_CVG_IgGM_Rep3 E11_5_CVG_IgGM
- GSM7437682 E11_5_CVG_H3K4me3_Rep1 E11_5_CVG_H3K4me3
- GSM7437683 E11_5_CVG_H3K4me3_Rep2 E11_5_CVG_H3K4me3
- GSM7437684 E11_5_CVG_H3K27me3_Rep1 E11_5_CVG_H3K27me3
- GSM7437685 E11_5_CVG_H3K27me3_Rep2 E11_5_CVG_H3K27me3
- GSM7437686 E11_5_CVG_H3K27me3_Rep3 E11_5_CVG_H3K27me3
- GSM7437687 E11_5_CVG_H3K27ac_Rep1 E11_5_CVG_H3K27ac
- GSM7437688 E11_5_CVG_H3K27ac_Rep2 E11_5_CVG_H3K27ac
- GSM7437689 E11_5_CVG_H3K27ac_Rep3 E11_5_CVG_H3K27ac
- GSE275333 MeCP2 Interacts with the Super Elongation Complex to Regulate Transcription 68 samples shares interact, regulate
- GSE318434 Endothelial TGFβ signaling regulates choroidal neovascularization severity via myeloid–endothelial interaction 40 samples shares interact, regulate
- GSE296778 Type 2 cytokines pleiotropically modulate sensory nerve architecture and neuroimmune interactions to mediate itch [Mouse ear pinnae] 20 samples shares interact, sensory
- GSE316171 Fibroblast Growth Factor Receptor Signaling in Maturing Osteoblasts Controls Cell-Matrix Interactions Critical for Osteocyte Survival 8 samples shares interact, survival
- GSE301940 CUT&Tag analysis of Isl1CKO and control pancreatic endocrine cells 11 samples shares isl1
- GSE287375 CTCF-RNA interactions orchestrate cell-specific chromatin loop organization [ChIP-seq] 54 samples shares interact
- GSE269027 Complex interaction of tumor-derived factors instructs the niche specific phenotypes of tumor-associated macrophages (in vitro ATAC-Seq) 27 samples shares interact
- GSE268623 Dynamic Foxp3-chromatin interaction controls tunable Treg cell function [Cut&Run Foxp3 Batf Ets1] 24 samples shares interact
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.