GEO series
Dietary tyramine promotes colon cancer risk and development via increased DNA damage and enhanced Inflammation [HCT116]
GSE233876
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2025/03/05
GPL20301
Summary
High dietary consumption of red or processed meat is associated with increased risk of colorectal cancer (CRC), likely through the presence of dietary carcinogens. Tyramine is a biogenic amine commonly found in processed food and can be produced by the gut bacteria from tyrosine. However, the role of tyramine in intestinal mucosal health has not been studied. Therefore, we used the human colonic HCT116 cell line to investigate the role of tyramine in modulating CRC risk and development
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Paper (PMID 40022152) ↗
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