GEO series
RNA sequencing of spheroids from HUVECs for differences in Cis- and Trans-signaling of IL-11
GSE234142
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2024/09/20
GPL30173
Summary
Cytokines of the IL-6 family, such as IL-11, may influence angiogenesis. Our experiments showed opposite angiogenic effects on HUVECs depending on cis- or transsignaling of IL-11. Spheroids from the 3D angiogenesis model (spheroid sprouting assay) were lysed in QIAzole buffer by vigorous vortexing. The transcriptomic changes were analyzed by RNA sequencing.
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Paper (PMID 39294742) ↗
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