GEO series
Blood transcriptional response to treatment-resistant depression during electroconvulsive therapy
GSE234669
Homo sapiens
Expression profiling by high throughput sequencing
35 samples
2024/06/30
GPL20301
Summary
This study aimed to elucidate the transcriptional differences in peripheral blood mononuclear cells (PBMC) between individuals with treatment-resistant depression (TRD) and a control group without a psychiatric illness; and between patients with TRD, treated with either standard antidepressant drugs alone, or in combination with electroconvulsive therapy (ECT) or ketamine. Additionally, PBMC transcriptomics were compared between treatment responders, following completion of their treatment protocols. PBMC transcriptomics were compared between treatment responders, following completion of their treatment protocols.
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Paper (PMID 34182381) ↗
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