GEO series
Multi-omic analysis of NCOR SMRT function in macrophages
GSE235408
Mus musculus
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
72 samples
2025/09/24
GPL13112GPL30172GPL24247
Summary
To compare NCOR and SMRT transcriptional repressor complexes in macrophages, we conducted an analysis of protein binding patterns, transcriptomic patterns, and epigenome correlations. Our systematic research revealed both the similarities and functional specificities of NCOR and SMRT, highlighting the synergistic and differential regulation characteristics of these complexes in macrophages. These findings offer a deeper understanding of the distinct manifestations of epigenome differential regulation.
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Paper (PMID 40966497) ↗
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