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Conversion of mouse fibroblast to hepatocyte-like cells by defined factors

GSE23635 Mus musculus Expression profiling by array 13 samples Submitted 2011/05/11 Platform GPL4134
Summary
Plasticity of differentiated cells has been proved by nuclear transfer, induced pluripotent cells and transdifferentiation. Here we show that by transduction of 3 factors (Hnf1alpha, Gata4, and Foxa3) and p19Arf inactivation, tail-tip fibroblasts can be converted to hepatocyte-like (iHep) cells, expressing hepatocyte marker genes, and acquiring many mature hepatocyte functions in vitro and in vivo.
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Also filed as BioProject PRJNA130939. Searching any of these in the dataset finder brings you back here.

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