TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy
DNA methylation · human · 14 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Topic
- Cervical cancerThis series is part of our curated briefing on it.
- Samples
- 14 samples: 3 × Case9 TET vs 3 × Wild vs 3 × [RNA-Seq] Wild vs 3 × [RNA-Seq] Case9 TETGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagyEpigenetics · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE236397_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA990741 and SRA study SRP446857. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 14 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7527896 Case9 TET-3 Case9 TET
- GSM7527897 Case9 TET-4 Case9 TET
- GSM7527898 Case9 TET-5 Case9 TET
- GSM7527899 Case9 TET input
- GSM7527900 Wild-1 Wild
- GSM7527901 Wild-2 Wild
- GSM7527902 Wild-3 Wild
- GSM7527903 Wild-input
- GSM7529968 [RNA-Seq] Wild-1 [RNA-Seq] Wild
- GSM7529969 [RNA-Seq] Wild-2 [RNA-Seq] Wild
- GSM7529970 [RNA-Seq] Wild-3 [RNA-Seq] Wild
- GSM7529971 [RNA-Seq] Case9 TET-3 [RNA-Seq] Case9 TET
- GSM7529973 [RNA-Seq] Case9 TET-4 [RNA-Seq] Case9 TET
- GSM7529974 [RNA-Seq] Case9 TET-5 [RNA-Seq] Case9 TET
- GSE279947 BAG2 inhibits the proliferation and migration of cervical cancer by slowing the degradation of STING 6 samples same disease briefing · shares migration, inhibits, cervical
- GSE318000 Lnc-GATS-3:3/MCM7 promotes the proliferation and invasion of cervical squamous cell carcinoma cells by regulating the CDK/Rb/E2F signaling pathway 8 samples same disease briefing · shares regulating, invasion, cervical
- GSE306495 Elevated VAMP8 Expression Promotes Cervical Cancer Progression by Enhancing Autophagy via HIF-1 Pathway 12 samples same disease briefing · shares autophagy, cervical
- GSE284355 Silencing of STEAP3 suppresses cervical cancer cell proliferation and migration via JAK/STAT3 signaling pathway 6 samples same disease briefing · shares migration, cervical
- GSE215288 LGALS1 plays an anti-oncogenic role in cervical cancer by synthetically regulating transcriptome profile in HeLa cells 4 samples same disease briefing · shares regulating, cervical
- GSE316098 Spatial Transcriptomic Landscape of Invasion Patterns in Human Papillomavirus-Associated Endocervical Adenocarcinoma 186 samples same disease briefing · shares invasion, cervical
- GSE168244 Patient-derived organoids as a platform to study cervical cancer and viral infection 36 samples same disease briefing · shares cervical
- GSE299125 Paracrine Signals from HIV-1 Infected Immune Cells Reprogram Cervical Cancer Pathways 35 samples same disease briefing · shares cervical
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.