GEO series
RNA-seq gene expression profile of SUM159PT breast cancer cell line upon manipulation of two TDMD triggers, NREP and SERPINE1
GSE236783
Homo sapiens
Expression profiling by high throughput sequencing
16 samples
2026/06/30
GPL24676
Summary
We investigate the effect of the perturbation of two transcripts involved in target-dependent microRNA degradation (TDMD): NREP is a trigger for miR-29b; SERPINE1 is a trigger for miR-30. We perturbed the genes and monitored the activity of miR-29 or miR-30 analysing the expression changes of their predicted target genes by RNA sequencing.
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