M1 Macrophages cause cardiac arrhythmia in an in vitro hiPSC coculture model of inflammation-induced atrial fibrillation
RNA-seq (gene expression) · human · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Immune response caused by M1 macrophages elicits atrial fibrillation-like phenotypes in coculture model with isogenic hiPSC-derived cardiomyocytesStem cell research & therapy · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE236870_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA992545 and SRA study SRP448030. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 24 more — browse all 24 samples with per-sample file links →
- GSE255992 Large-scale Single-nuclei Profiling Identifies Role for ATRNL1 in Atrial Fibrillation 49 samples shares fibrillation, atrial
- GSE313106 Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias 48 samples shares arrhythmia, cardiac
- GSE255612 Large-scale Single-nuclei Profiling Identifies Role for ATRNL1 in Atrial Fibrillation [snRNA-seq] 34 samples shares fibrillation, atrial
- GSE282504 Using integrative bioinformatics approaches and machine‑learning strategies to Identify potential signatures for atrial fibrillation 30 samples shares fibrillation, atrial
- GSE269882 The role of structural vs cellular remodeling in arrhythmogenesis: personalized computer models of atrial fibrillation 27 samples shares fibrillation, atrial
- GSE261170 Single Cell Landscape of Left Atria Reveals Amphiregulin and Insulin-like Growth Factor 1 as Surrogate Markers in Patients with Atrial Fibrillation. 15 samples shares fibrillation, atrial
- GSE255991 Large-scale Single-nuclei Profiling Identifies Role for ATRNL1 in Atrial Fibrillation [bulk RNA-seq] 15 samples shares fibrillation, atrial
- GSE238242 Atrial fibrillation variant-to-gene prioritization through cross-ancestry eQTL and single-nucleus multiomic analyses 14 samples shares fibrillation, atrial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.