GEO series
Herpes simplex virus type 1 reshapes the host chromatin architecture via transcription machinery hijacking [RNA-seq]
GSE237079
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/05/12
GPL23227
Summary
To discover the mechanism by which herpes simplex virus type 1 (HSV-1) drastically reshapes the host cell transcriptional patterns during infection, we performed RNAseq. We infected A549 cells with HSV-1, and analized host and viral expression at 1, 3 and 8 hours post infection. We report both a drastical human transcription shutoff parallel with an increase in viral transcription.
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Paper (PMID 40537528) ↗
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