Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2- dependent transcription of Ifng
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 58 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 58 samples: 46 distinct titles, 4 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of IfngImmunity · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE237643_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA996077 and SRA study SRP450134. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 1 samples read as cases, 34 as controls.
How we read this: Read from 58 sample titles: 46 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7635033 WT_Ctl, rep 1, ATACseq
- GSM7635034 WT_Ctl, rep 2, ATACseq
- GSM7635035 WT_Ctl, rep 3, ATACseq
- GSM7635036 WT_Sti, rep 1, ATACseq
- GSM7635037 WT_Sti, rep 2, ATACseq
- GSM7635038 WT_Sti, rep 3, ATACseq
- GSM7635039 KO_Ctl, rep 1, ATACseq
- GSM7635040 KO_Ctl, rep 2, ATACseq
- GSM7635041 KO_Ctl, rep 3, ATACseq
- GSM7635042 KO_Sti, rep 1, ATACseq
- GSM7635043 KO_Sti, rep 2, ATACseq
- GSM7635044 KO_Sti, rep 3, ATACseq
- GSM7635045 WT,GEX, L1
- GSM7635046 WT,GEX, L2
- GSM7635047 WT,GEX, L3
- GSM7635048 WT,GEX, L4
- GSM7635049 WT, ADT,L1
- GSM7635050 WT, ADT,L2
- GSM7635051 WT, ADT,L3
- GSM7635052 WT, ADT,L4
- GSM7635053 KO, GEX, L1
- GSM7635054 KO, GEX, L2
- GSM7635055 KO, GEX, L3
- GSM7635056 KO, GEX, L4
- GSM7635057 KO, ADT, L1
- GSM7635058 KO, ADT, L2
- GSM7635059 KO, ADT, L3
- GSM7635060 KO, ADT, L4
- GSM7635061 WT_Input, rep 1, ChIPseq
- GSM7635062 WT_Input, rep 2, ChIPseq
- GSM7635063 WT_ChIP, rep 1, ChIPseq
- GSM7635064 WT_ChIP, rep 2, ChIPseq
- GSM7635065 KO_Input, rep 1, ChIPseq
- GSM7635066 KO_Input, rep 2, ChIPseq
- GSM7635067 KO_ChIP, rep 1, ChIPseq
- GSM7635068 KO_ChIP, rep 2, ChIPseq
- GSM7635069 WT_Input, rep 3, ChIPseq
- GSM7635070 WT_ChIP, rep 3, ChIPseq
- GSM7635071 KO_Input, rep 3, ChIPseq
- GSM7635072 KO_ChIP, rep 3, ChIPseq
+ 18 more — browse all 58 samples with per-sample file links →
- GSE297195 Age-dependent Transcriptional and Circuit Alterations in the brain Underlie Post-Anesthesia Neurobehavioral Dysfunction 66 samples shares transcription, dependent
- GSE266584 Epigenetic and transcriptional regulation of dendritic cell development and anti-tumor function by HDAC1 34 samples shares transcription, anti-tumor
- GSE229592 Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity 32 samples shares transcription, anti-tumor
- GSE245838 Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity [mouse scRNA-seq] 21 samples shares transcription, anti-tumor
- GSE200323 Establishment of chromatin architecture interplays with embryo hypertranscription 158 samples shares transcription
- GSE284504 Transcriptional profiling of brain from a zQ175 KI mouse model of Huntington's disease 335 samples shares transcription
- GSE237534 INO80 / SWR remodelers regulate Pol II transcription through BRD2 and chromatin landscape 217 samples shares transcription
- GSE294772 Single-Cell Epigenomics Uncovers Heterochromatin Instability and Transcription Factor Dysfunction during Mouse Brain Aging [snATAC-Seq] [10X Multiome] 142 samples shares transcription
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.