ZBTB48 is a pioneer factor regulating B-cell-specific CIITA expression.
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 36 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 36 samples: 10 conditions, mostly with about 5 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- ZBTB48 is a priming factor regulating B-cell-specific CIITA expressionThe EMBO journal · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE237959_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA997296 and SRA study SRP450804. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 34 samples.
How we read this: 10 replicated groups read from 36 sample titles; they account for 34 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7656923 U2OS cells, WT H3K4me3 ChIP, rep1 U2OS cells, WT H3K4me3 …
- GSM7656924 U2OS cells, WT H3K4me3 ChIP, rep2 U2OS cells, WT H3K4me3 …
- GSM7656925 U2OS cells, WT H3K4me3 ChIP, rep3 U2OS cells, WT H3K4me3 …
- GSM7656926 U2OS cells, ZBTB48 KO H3K4me3 ChIP, rep1 U2OS cells, ZBTB48 KO H…
- GSM7656927 U2OS cells, ZBTB48 KO H3K4me3 ChIP, rep2 U2OS cells, ZBTB48 KO H…
- GSM7656928 U2OS cells, ZBTB48 KO H3K4me3 ChIP, rep3 U2OS cells, ZBTB48 KO H…
- GSM7656929 U2OS cells, WT input, rep1 U2OS cells, WT input,
- GSM7656930 U2OS cells, WT input, rep2 U2OS cells, WT input,
- GSM7656931 U2OS cells, WT FAIRE, rep1 U2OS cells, WT FAIRE,
- GSM7656932 U2OS cells, WT FAIRE, rep2 U2OS cells, WT FAIRE,
- GSM7656933 U2OS cells, ZBTB48 KO FAIRE, rep1 U2OS cells, ZBTB48 KO F…
- GSM7656934 U2OS cells, ZBTB48 KO FAIRE, rep2 U2OS cells, ZBTB48 KO F…
- GSM7656935 U2OS cells, WT IFNg FAIRE, rep1 U2OS cells, WT IFNg FAI…
- GSM7656936 U2OS cells, WT IFNg FAIRE, rep2 U2OS cells, WT IFNg FAI…
- GSM7656937 U2OS cells, ZBTB48 KO IFng FAIRE, rep1
- GSM7656938 U2OS cells, ZBTB48 KO IFNg FAIRE, rep2
- GSM7656939 U2OS cells, WT, RNA-seq rep1 U2OS cells, WT, RNA-seq
- GSM7656940 U2OS cells, WT, RNA-seq rep2 U2OS cells, WT, RNA-seq
- GSM7656941 U2OS cells, WT, RNA-seq rep3 U2OS cells, WT, RNA-seq
- GSM7656942 U2OS cells, WT, RNA-seq rep4 U2OS cells, WT, RNA-seq
- GSM7656943 U2OS cells, WT, RNA-seq rep5 U2OS cells, WT, RNA-seq
- GSM7656944 U2OS cells, ZBTB48 KO, RNA-seq rep1 U2OS cells, ZBTB48 KO, …
- GSM7656945 U2OS cells, ZBTB48 KO, RNA-seq rep2 U2OS cells, ZBTB48 KO, …
- GSM7656946 U2OS cells, ZBTB48 KO, RNA-seq rep3 U2OS cells, ZBTB48 KO, …
- GSM7656947 U2OS cells, ZBTB48 KO, RNA-seq rep4 U2OS cells, ZBTB48 KO, …
- GSM7656948 U2OS cells, ZBTB48 KO, RNA-seq rep5 U2OS cells, ZBTB48 KO, …
- GSM7656949 U2OS cells, WT IFNg, RNA-seq rep1 U2OS cells, WT IFNg, RN…
- GSM7656950 U2OS cells, WT IFNg, RNA-seq rep2 U2OS cells, WT IFNg, RN…
- GSM7656951 U2OS cells, WT IFNg, RNA-seq rep3 U2OS cells, WT IFNg, RN…
- GSM7656952 U2OS cells, WT IFNg, RNA-seq rep4 U2OS cells, WT IFNg, RN…
- GSM7656953 U2OS cells, WT IFNg, RNA-seq rep5 U2OS cells, WT IFNg, RN…
- GSM7656954 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep1 U2OS cells, ZBTB48 KO I…
- GSM7656955 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep2 U2OS cells, ZBTB48 KO I…
- GSM7656956 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep3 U2OS cells, ZBTB48 KO I…
- GSM7656957 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep4 U2OS cells, ZBTB48 KO I…
- GSM7656958 U2OS cells, ZBTB48 KO IFNg, RNA-seq rep5 U2OS cells, ZBTB48 KO I…
- GSE237958 ZBTB48 is a pioneer factor regulating B-cell-specific CIITA expression [RNA-seq] 20 samples shares zbtb48, ciita, b-cell-specific, regulating, pioneer, factor
- GSE301298 Functional redundancy between UTY and UTX in regulating the localization of transcription factors involved in pluripotency 88 samples shares regulating, factor
- GSE324163 Kava and DHM inhibit chronic hexavalent chromium exposure-induced cell malignant transformation through down-regulating RNA splicing factor SNRPA1 expression 12 samples shares regulating, factor
- GSE301297 Functional redundancy between UTY and UTX in regulating the localization of transcription factors involved in pluripotency [RNA-seq] 40 samples shares regulating, factor
- GSE301295 Functional redundancy between UTY and UTX in regulating the localization of transcription factors involved in pluripotency [ChIP-seq_dualcross] 38 samples shares regulating, factor
- GSE264191 Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2 and CD44 through NFκB signaling 30 samples shares regulating, factor
- GSE251851 Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2 and CD44 through NFκB signaling [LNCaP] 18 samples shares regulating, factor
- GSE279376 Exploring the Factors regulating RNA Enrichment in EVs 12 samples shares regulating, factor
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.