Transcriptome profile of HeLa COL1G610C transfected cells compared to control cells
RNA-seq (gene expression) · human · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 10 samples: 5 × HeLa_WT_SC vs 5 × HeLa_WT_COL1Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Sestrin2 drives ER-phagy in response to protein misfoldingDevelopmental cell · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE239525_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA999654 and SRA study SRP451976. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 2 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7666884 HeLa_WT_SCR_1 HeLa_WT_SC
- GSM7666885 HeLa_WT_SCR_2 HeLa_WT_SC
- GSM7666886 HeLa_WT_SCR_3 HeLa_WT_SC
- GSM7666887 HeLa_WT_SCR_4 HeLa_WT_SC
- GSM7666888 HeLa_WT_SCR_5 HeLa_WT_SC
- GSM7666889 HeLa_WT_COL1_1 HeLa_WT_COL1
- GSM7666890 HeLa_WT_COL1_2 HeLa_WT_COL1
- GSM7666891 HeLa_WT_COL1_3 HeLa_WT_COL1
- GSM7666892 HeLa_WT_COL1_4 HeLa_WT_COL1
- GSM7666893 HeLa_WT_COL1_5 HeLa_WT_COL1
- GSE211032 Expression Analysis (RNA-Seq) of adult Myelodysplastic Syndromes (MDS)/Acute Myeloid Leukemia (AML) with isolated monosomy 7 compared to controls 45 samples shares compared, control
- GSE306607 RNA sequencing of HeLa cells with scramble control and CNOT11 knockdown 4 samples shares control, hela
- GSE98793 Gene expression analysis in whole blood samples obtained from donors diagnosed with MDD compared to healthy controls 192 samples shares compared, control
- GSE270484 Patchseq Data of T1D Donor Islets vs ND Matched Controls 958 samples shares control
- GSE305811 Immune and Transcriptional Landscape of Endometrial Receptivity at P+5 Phase: A Triad Analysis of EIN, RIF, and Control Endometrial Profiles 92 samples shares control
- GSE161245 Comparison of bronchial epithelial cells obtained by bronchoscopy from mild asthma patients, moderate asthma patients, severe asthma patients and healthy controls 55 samples shares control
- GSE288682 control versus allergic rhinitis basal cells in response to Der p1 36 samples shares control
- GSE252145 Transcriptomic Profile of Breast Tissue of Premenopausal Women Following Treatment with Progesterone Receptor Modulator: Secondary Outcomes of a Randomized Controlled Trial 32 samples shares control
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.