GEO series
Aedes aegypti NeSt1 interacts with human CD47 to enhance Zika virus infectivity
GSE239840
Homo sapiens
Expression profiling by high throughput sequencing
64 samples
2024/12/05
GPL20301
Summary
Aedes aegypti is a vector of many infectious agents, including flaviviruses like Zika virus. We demonstrate that Nest1, a 34kDa mosquito salivary protein, facilitates Zika virus dissemination in human skin explants. Our aim was to analyze the effect of Nest1 at a transcriptomic level (RNAseq) in human skin explants, in the presence and absence of virus (ZIKV), at different timepoints (day 1, 2,3 ,and 4)
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Paper (PMID 39121194) ↗
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