← BioTransfer GEO Dataset Finder
GEO series

Transcriptomic profiling of human alveolar organoids(hALOs)

GSE240203 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/08/06 Platform GPL24676
Summary
We performed global transcriptomic profiling of hALOs at early (P4), middle (P13) and late (P20) passages and found that the transcripts of the hALOs were similar to that of primary lung progenitor organoids.hALOs highly expressed genes associated with lung development/lung progenitor, AT2 specification and AT1 specification.We found that our hALOs were more similar to pseudoglandular-staged lung.The gene sets associated with alveolar maturation, such as surfactant homeostasis or response to oxygen levels, were upregulated in P20. Besides, genes involved in endoderm development or respiratory tube development were downregulated
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE240203_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1002798 and SRA study SRP453627. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.