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The molecular mechanism responsible for HbSC retinopathy may depend on the action of angiogenesis-related genes ROBO1 and SLC38A5.

GSE240446 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/08/09 Platform GPL16791
Summary
Purpose: HbSC disease, a less severe form of sickle cell disease, affects the retina more frequently and patients have higher rates of proliferative retinopathy that can progress to vision loss. This study aimed to identify differences in the expression of endothelial cell-derived molecules associated with pathophysiology of proliferative sickle cell retinopathy (PSCR).
Published in
The molecular mechanism responsible for HbSC retinopathy may depend on the action of the angiogenesis-related genes ROBO1 and SLC38A5
da Silva Costa SM, Ito MT, da Cruz PRS et al. · Experimental biology and medicine (Maywood, N.J.) 2024 · PMID 39114443 · doi:10.3389/ebm.2024.10070
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Also filed as BioProject PRJNA1003811 and SRA study SRP454207. Searching any of these in the dataset finder brings you back here.

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