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Enhancer-activated RET confers protection against oxidative stress to the MLL-rearranged acute myeloid leukemia cells

GSE241738 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/03/04 Platform GPL24676
Summary
RET expression is upregulated in AML subtypes harboring genetic fusions of MLL-1 genes compared to age-matched healthy donors and other AML subtypes. In addition, we identify a novel epigenetic mechanism of RET overexpression in MLL-rearranged AML.
Published in
Enhancer-activated RET confers protection against oxidative stress to KMT2A-rearranged acute myeloid leukemia
Frett B, Stephens KE, Koss B et al. · Cancer science 2024 · PMID 38226414 · doi:10.1111/cas.16069
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Also filed as BioProject PRJNA1009434 and SRA study SRP457245. Searching any of these in the dataset finder brings you back here.

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