Intrahepatic immune microenvironment contributes to spontaneous tolerance in pediatric liver transplantation recipients
RNA-seq (gene expression) · human · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 7 × Liver, low IS dosage/L, vs 7 × Liver, normal IS dosage/H, vs 4 × Liver, tolerant/T,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE242205_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1011976 and SRA study SRP458070. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 3 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7754997 Liver, tolerant/T, 1 Liver, tolerant/T,
- GSM7754998 Liver, tolerant/T, 2 Liver, tolerant/T,
- GSM7754999 Liver, tolerant/T, 3 Liver, tolerant/T,
- GSM7755000 Liver, tolerant/T, 4 Liver, tolerant/T,
- GSM7755001 Liver, low IS dosage/L, 1 Liver, low IS dosage/L,
- GSM7755002 Liver, low IS dosage/L, 2 Liver, low IS dosage/L,
- GSM7755003 Liver, low IS dosage/L, 3 Liver, low IS dosage/L,
- GSM7755004 Liver, low IS dosage/L, 4 Liver, low IS dosage/L,
- GSM7755005 Liver, low IS dosage/L, 5 Liver, low IS dosage/L,
- GSM7755006 Liver, low IS dosage/L, 6 Liver, low IS dosage/L,
- GSM7755007 Liver, low IS dosage/L, 7 Liver, low IS dosage/L,
- GSM7755008 Liver, normal IS dosage/H, 1 Liver, normal IS dosage…
- GSM7755009 Liver, normal IS dosage/H, 2 Liver, normal IS dosage…
- GSM7755010 Liver, normal IS dosage/H, 3 Liver, normal IS dosage…
- GSM7755011 Liver, normal IS dosage/H, 4 Liver, normal IS dosage…
- GSM7755012 Liver, normal IS dosage/H, 5 Liver, normal IS dosage…
- GSM7755013 Liver, normal IS dosage/H, 6 Liver, normal IS dosage…
- GSM7755014 Liver, normal IS dosage/H, 7 Liver, normal IS dosage…
- GSE248287 Remodeling of the immune microenvironment is linked to adverse outcome in pediatric T cell acute lymphoblastic leukemia 34 samples shares microenvironment, pediatric
- GSE264117 Investigating microenvironment in MDS II 503 samples shares microenvironment
- GSE309595 Longitudinal Analysis of Multiple Myeloma: Therapeutic Response and Immune Microenvironment Dynamics in the Context of Tumor Heterogeneity [scRNA-seq] 270 samples shares microenvironment
- GSE263733 Single-cell transcriptome analysis reveals subtype-specific clonal evolution and microenvironmental changes in liver metastasis of pancreatic adenocarcinoma and their clinical implications 218 samples shares microenvironment
- GSE310388 In situ multi-modal characterization of pancreatic cancer reveals tumor cell identity as a defining factor of the surrounding microenvironment. [RNA-Seq] 171 samples shares microenvironment
- GSE252272 RNA sequencing of CTOT19 transplantation patients [bulk RNA-seq] 130 samples shares transplantation
- GSE294016 A macrophage-predominant, immunosuppressive immune microenvironment and subtype-specific therapeutic vulnerabilities in advanced salivary gland cancer [bulk RNA-seq] 95 samples shares microenvironment
- GSE341455 Skeletal muscle reprogramming of metabolic, ribosomal and developmental pathways contributes to Roux-en-Y gastric bypass-induced adaptation in women 70 samples shares contributes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.