Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy
RNA-seq (gene expression) · human · 21 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 21 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophyiScience · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE242524_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1013808 and SRA study SRP459051. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 21 more — browse all 21 samples with per-sample file links →
- GSE300883 Endothelial PIEZO1 activation impairs osteogenesis via GREM1-mediated inhibition of BMP signaling [hBMEC_RNA-seq] 8 samples shares bmp, activation
- GSE248274 Vitamin D opposes multilineage cell differentiation induced by Notch inhibition and BMP pathway activation in human colon organoids 18 samples shares bmp, activation
- GSE341139 A conserved HAND2-BMP5-SMAD1/5/9 axis drives hepatic stellate cell activation and extracellular matrix overproduction in multiple fibrotic etiologies 10 samples shares bmp, activation
- GSE324566 RNA-seq of human articular chondrocytes after exposure to BMP7-derived peptide p[63-82]. 8 samples shares bmp, chondrocyte
- GSE269904 A temporal factorial dissection of kidney organoid differentiation identifies the impact of WNT, FGF, BMP and GDF signaling on ‘off-target’ patterning 30 samples shares bmp
- GSE229150 The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma 30 samples shares bmp
- GSE253785 Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid [RNA-seq] 17 samples shares bmp
- GSE246903 Netrin1 patterns the dorsal spinal cord through modulation of Bmp signaling 16 samples shares bmp
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.