Transcription factor ZNF263 primes human embryonic stem cells for pluripotency dissolution and early differentiation
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 81 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 81 samples: 62 distinct titles, 10 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transcription factor ZNF263 primes human embryonic stem cells for pluripotency dissolution and lineage commitmentNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE242906_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1015254 and SRA study SRP459532. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 81 sample titles: 62 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7771573 H1, WT, ZNF263 ENDO ChIP, rep1
- GSM7771574 H1, WT, ZNF263 ENDO ChIP, rep2
- GSM7771575 H1, WT, ZNF263 ENDO, input
- GSM7771576 H1, 1-10 KO, ZNF263 FLAG ChIP
- GSM7771577 H1, 1-10 KO, ZNF263 FLAG, input
- GSM7771578 H1, WT, H3K4me3 ChIP
- GSM7771579 H1, WT, H3K27ac ChIP
- GSM7771580 H1, WT, H3K27me3 ChIP
- GSM7771581 H1, WT, His, input
- GSM7771582 H1, 1-10 KO, H3K4me3 ChIP
- GSM7771583 H1, 1-10 KO, H3K27ac ChIP
- GSM7771584 H1, 1-10 KO, H3K27me3 ChIP
- GSM7771585 H1, 1-10 KO, His, input
- GSM7774579 H1, WT, no rep
- GSM7774580 H1, 1-5 KO, no rep
- GSM7774581 H1, 1-10 KO, no rep
- GSM7774582 H1, WT, rep1
- GSM7774583 H1, WT, rep2
- GSM7774584 H1, WT, rep3
- GSM7774585 H1, 1-10 KO, rep1
- GSM7774586 H1, 1-10 KO, rep2
- GSM7774587 H1, 1-10 KO, rep3
- GSM7774588 H9, WT, rep1
- GSM7774589 H9, WT, rep2
- GSM7774590 H9, WT, rep3
- GSM7774591 H9, 9-1 KO, rep1
- GSM7774592 H9, 9-1 KO, rep2
- GSM7774593 H9, 9-1 KO, rep3
- GSM7774594 H9, 9-D KO, rep1
- GSM7774595 H9, 9-D KO, rep2
- GSM7774596 H9, 9-D KO, rep3
- GSM7774597 H1, WT, scRNA
- GSM7774598 H1, 1-10 KO, scRNA
- GSM7852750 Zic2rep1,CUTTag,H1WT
- GSM7852751 Zic2rep2,CUTTag,H1WT
- GSM7852752 Zic2rep1,CUTTag,H1KO
- GSM7852753 Zic2rep2,CUTTag,H1KO
- GSM7852754 lgG,CUTTag,H1WT
- GSM7852755 lgG,CUTTag,H1KO
- GSM7915916 H1,WT,rep1,vehicle
+ 41 more — browse all 81 samples with per-sample file links →
- GSE301298 Functional redundancy between UTY and UTX in regulating the localization of transcription factors involved in pluripotency 88 samples shares transcription, pluripotency, factor
- GSE295823 Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer 20 samples shares transcription, factor
- GSE196619 Synthetic transcription factor overrides persistent repressive chromatin marks 120 samples shares transcription, factor
- GSE302930 Epigenetic Atlas of Bladder Cancer Reveals Master Transcription Factors and Risk-Associated Regulatory Elements in Luminal and Basal-Squamous Molecular Subtypes 92 samples shares transcription, factor
- GSE283600 LINE-1 transposable elements regulate the exit of human pluripotency and early brain development 83 samples shares pluripotency, early
- GSE245175 Neuroblastoma heterogeneity and plasticity over disease progression are rooted in the dynamics of an early sympathetic transcriptional trajectory 79 samples shares transcription, early
- GSE275721 Lineage master regulator and cancer-selective partner transcription factors rewire 3D genome topology for tumor-specific gene control 72 samples shares transcription, factor
- GSE335058 Evolutionary guided transcription factor design programs novel T cell states [ChIP-Seq] 66 samples shares transcription, factor
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.