Aberrant pace of cortical neuron development in brain organoids from patients with 22q11.2 deletion syndrome and schizophrenia.
Non-coding RNA profiling · human · 26 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 26 samples: 24 distinct titles, 2 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Aberrant pace of cortical neuron development in brain organoids from patients with 22q11.2 deletion syndrome-associated schizophreniaNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244010_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA1020883 and SRA study SRP463075. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 26 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7804653 Q2, control, 70DIV
- GSM7804654 Q1, case, 70DIV
- GSM7804655 Q5, control, 70DIV
- GSM7804656 Q6, case, 70DIV
- GSM7804657 QR20, control, 70DIV
- GSM7804658 QR27, case, 70DIV
- GSM7804659 Q2, control
- GSM7804660 Q1, case
- GSM7804661 Q5, control, 150DIV
- GSM7804662 Q6, case, 150DIV
- GSM7804663 QR20, control, 150DIV
- GSM7804664 QR27, case, 150DIV
- GSM7804665 Q2 - control
- GSM7804666 Q1 - case
- GSM7804667 Q5 - control
- GSM7804668 Q6 - case
- GSM7804669 QR19 - control
- GSM7804670 QR23 - case
- GSM7804671 QR20 - control
- GSM7804672 QR27 - case
- GSM7804673 Q1, case
- GSM7804674 Q2, control
- GSM7804675 Q5, control
- GSM7804676 Q6, case
- GSM7804677 QR20, control
- GSM7804678 QR27, case
- GSE311978 Downregulated transcription in chromosomal domains of midbrain dopamine neurons linked to schizophrenia. [RNA-Seq] 97 samples shares schizophrenia, neuron, brain
- GSE289912 APOE4 impacts cortical neurodevelopment and alters network formation in human brain organoids 32 samples shares organoids, cortical, brain
- GSE303979 JAX Study 11- RNA-seq of male KOLF2.2J hiPSC-derived cortical brain organoids during different time points. 18 samples shares organoids, cortical, brain
- GSE277967 Reconstitution of Human Brain Cell Diversity in Organoids via Four Protocols [time-course bulk RNA-seq] 768 samples shares organoids, brain
- GSE301365 Single-cell analysis of human iPSC-derived midbrain organoids generated with triphasic Wnt modulation combined with a dynamic bioreactor 30 samples shares organoids, brain
- GSE231321 Phosphorylation of 53BP1 by ATM enforce neurodevelopmental programs in cortical organoids 30 samples shares organoids, cortical
- GSE278808 Mutations of schizophrenia risk gene SETD1A dysregulate synaptic function in human neurons 26 samples shares schizophrenia, neuron
- GSE197887 Single-cell RNA sequencing of human forebrain organoids from typical and autism subjects 25 samples shares organoids, brain
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.