Lenalidomide-induced pure red cell aplasia: clinical characteristics and mechanistic analysis
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 11 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244045_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1021157 and SRA study SRP463329. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 2 samples read as cases, 8 as controls.
How we read this: Read from 12 sample titles: 11 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7805820 erythroblast,healthy donor,DMSO,rep1
- GSM7805821 erythroblast,healthy donor,DMSO,rep2
- GSM7805822 erythroblast,healthy donor,lenalidomide,rep1
- GSM7805823 erythroblast,healthy donor, lenalidomide,rep2
- GSM7805824 erythroblast,PRCA,,DMSO,rep1
- GSM7805825 erythroblast,PRCA ,DMSO,rep2
- GSM7805826 erythroblast,PRCA ,lenalidomide,rep1
- GSM7805827 erythroblast,PRCA, lenalidomide,rep2
- GSM7805828 BMMNCs,healthy donor,rep1
- GSM7805829 BMMNCs,healthy donor,rep2-4 merge
- GSM7805830 BMMNCs,PRCA patient ,partially recover(P3)
- GSM7805831 BMMNCs,PRCA patient,relapse(P4)
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.