Chondrodysplasia-inducing COL2A1 p.Gly1170Ser causes an ER storage defect without associated unfolded protein response in chondronoids
RNA-seq (gene expression) · human · 78 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 78 samples: 77 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- ER procollagen storage defect without coupled unfolded protein response drives precocious arthritisLife science alliance · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244375_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1022488 and SRA study SRP463925. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 78 sample titles: 77 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7814385 WT 1-1 e
- GSM7814386 WT 1-2 e
- GSM7814387 WT 1-3 e
- GSM7814388 WT 1-4 e
- GSM7814389 WT 2-1 e
- GSM7814390 WT 2-2 e
- GSM7814391 WT 2-3 e
- GSM7814392 WT 2-4 e
- GSM7814393 WT 3-1 e
- GSM7814394 WT 3-2 e
- GSM7814395 WT 3-3 e
- GSM7814396 WT 3-4 e
- GSM7814397 Het 1-1 e
- GSM7814398 Het 1-2 e
- GSM7814399 Het 1-3 e
- GSM7814400 Het 1-4 e
- GSM7814401 Het 2-1 e
- GSM7814402 Het 2-2 e
- GSM7814403 Het 2-3 e
- GSM7814404 Het 2-4 e
- GSM7814405 Het 3-1 e
- GSM7814406 Het 3-2 e
- GSM7814407 Het 3-3 e
- GSM7814408 Het 3-4 e
- GSM7814409 Hom 1-1 e
- GSM7814410 Hom 1-2 e
- GSM7814411 Hom 1-3 e
- GSM7814412 Hom 1-4 e
- GSM7814413 Hom 2-1 e
- GSM7814414 Hom 2-2 e
- GSM7814415 Hom 2-3 e
- GSM7814416 Hom 2-4 e
- GSM7814417 Hom 3-1 e
- GSM7814418 Hom 3-2 e
- GSM7814419 Hom 3-3 e
- GSM7814420 Hom 3-4 e
- GSM7814421 WT 1-1 l
- GSM7814422 WT 1-2 l
- GSM7814423 WT 1-3 l
- GSM7814424 WT 1-4 l
+ 38 more — browse all 78 samples with per-sample file links →
No close match found for this topic, so these are simply the most-viewed datasets of the same kind.
- GSE309595 Longitudinal Analysis of Multiple Myeloma: Therapeutic Response and Immune Microenvironment Dynamics in the Context of Tumor Heterogeneity [scRNA-seq] 270 samples
- GSE178411 Whole-transcriptome analysis illustrates evolving transcriptional human response to injury in acute wounds and scars 108 samples
- GSE330697 Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle 93 samples
- GSE339456 Integrated bulk and spatial transcriptomic analysis identifies progression-associated molecular signatures in biopsy-proven hypertensive nephropathy [RNA-seq] 35 samples
- GSE298464 Single-cell RNA sequencing reveals ulcerative colitis patients’ response to anti-TNF-α therapy 16 samples
- GSE314342 Genome-scale perturb-seq in primary human CD4+ T cells reveals genes regulating T cell programs and human immune traits. 577 samples
- GSE205672 Transcriptomes of human PBMCs and monocytes in sepsis patients 460 samples
- GSE319641 RNA-Seq profiling of pre- and on-treatment tumor samples from breast cancer patients enrolled in the NeoTRIP trial. 401 samples
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.