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Binding Changes in Chromatin Factors Upon Targeted XPO1 Inhibition in T Cells

GSE244396 Homo sapiens Other; Genome binding/occupancy profiling by high throughput sequencing 20 samples 2024/05/07 GPL24676
Summary
We assessed the chromatin localization of XPO1 and p300 in response to C646 (10 uM), S109 (1 uM), and SP100030 (1 uM). We used CUT&RUN sequencing as a lower-input (500,000 cells per sample), higher-sensitivity alternative to ChIP-Seq to assess chromatin binding of different factors
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