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The CGG triplet repeat binding protein 1 counteracts DNA secondary structure formation to prevent transcription-replication stress

GSE244415 Homo sapiens Expression profiling by high throughput sequencing; Other 8 samples Submitted 2025/02/01 Platform GPL24676
Summary
CGGBP1 has been implicated in transcription regulation. We tried to investigate the molecular mechanism of how transcription is regulated by depletion of CGGBP1 protein.
Published in
The CGG triplet repeat binding protein 1 counteracts R-loop induced transcription-replication stress
Ummethum H, Murriello AC, Werner M et al. · EMBO reports 2025 · PMID 40859011 · doi:10.1038/s44319-025-00550-1
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Also filed as BioProject PRJNA1022814 and SRA study SRP464027. Searching any of these in the dataset finder brings you back here.

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