Assessment of myogenic maturation for human iPSC-derived iPAX7 myogenic progenitors in vitro and in vivo
RNA-seq (gene expression) · human · 14 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 14 samples: 5 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The adult environment promotes the transcriptional maturation of human iPSC-derived muscle graftsNPJ Regenerative medicine · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244521_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1023472 and SRA study SRP464293. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 5 replicated groups read from 14 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7818598 NSG-mdx control Replicate 1 NSG-mdx control
- GSM7818599 NSG-mdx control Replicate 2 NSG-mdx control
- GSM7818600 NSG-mdx control Replicate 3 NSG-mdx control
- GSM7818601 NSG-mdx iPAX7 Replicate 1 NSG-mdx iPAX7
- GSM7818602 NSG-mdx iPAX7 Replicate 2 NSG-mdx iPAX7
- GSM7818603 NSG-mdx iPAX7 Replicate 3 NSG-mdx iPAX7
- GSM7818604 NSG control Replicate 1 NSG control
- GSM7818605 NSG control Replicate 2 NSG control
- GSM7818606 NSG control Replicate 3 NSG control
- GSM7818607 NSG iPAX7 Replicate 1 NSG iPAX7
- GSM7818608 NSG iPAX7 Replicate 2 NSG iPAX7
- GSM7818609 NSG iPAX7 Replicate 3 NSG iPAX7
- GSM7818610 iPAX7 in vitro Replicate 1 iPAX7 in vitro
- GSM7818611 iPAX7 in vitro Replicate 2 iPAX7 in vitro
- GSE312133 Intrinsic mechanisms and microenvironmental cues fine-tune plasticity of esophageal progenitors 26 samples shares progenitors
- GSE294342 ALDH1A1+ cells are endometrial progenitors contributing to regeneration and endometriosis 20 samples shares progenitors
- GSE312740 Immune response to adeno-associated viral vectors in a human iPSC-derived microglia chimeric mouse model 16 samples shares ipsc-derived
- GSE232586 Compared with the Mock group, FGF8+10 treatment mature the differentiated LPM-like cells to form LM-like cells, and gene expression profile at single cell level of Msx1+ mesenchymal progenitors from mouse E10.5 embryos 9 samples shares progenitors
- GSE293298 Expression of synaptic function genes in iPSC-derived induced human neurons 2 samples shares ipsc-derived
- GSE259430 Human iPSC-derived cell grafts promote functional recovery by molecular interaction with stroke-injured brain 1 samples shares ipsc-derived
- GSE218430 LncRNA SNHG26 facilitates inflammatory to proliferative state transition of keratinocyte progenitors during wound healing 17 samples shares progenitors
- GSE46631 Vascularised and functional human liver from an iPSC-derived organ bud transplant 13 samples shares ipsc-derived
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.