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Transcriptomic profiling of 2 cell lines from Down-Syndrome children with Acute Lymphoblastic Leukaemia (DS-ALL)

GSE245056 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2024/07/10 Platform GPL24676
Summary
Two cell lines derived from 2 Down Syndrome children who developed Acute Lymphoblastic Leukaemia were profiled at the transcriptomic level (bulk RNAseq) and compared against their Patient-Derived Xenograft (PDX) of origin.
Published in
Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia
Carey-Smith SL, Simad MH, Panchal K et al. · Haematologica 2024 · PMID 38426275 · doi:10.3324/haematol.2023.284271
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Also filed as BioProject PRJNA1026868 and SRA study SRP465604. Searching any of these in the dataset finder brings you back here.

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