Inter-individual variations in circadian misalignment-induced NAFLD pathophysiology in mice
RNA-seq (gene expression) · mouse · 41 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 41 samples: 23 × A vs 18 × LGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Inter-individual variations in circadian misalignment-induced NAFLD pathophysiology in miceiScience · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE245519_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1028642 and SRA study SRP466628. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 41 samples.
How we read this: 2 replicated groups read from 41 sample titles; they account for 41 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7844335 A01 A
- GSM7844336 A02 A
- GSM7844337 A03 A
- GSM7844338 A04 A
- GSM7844339 A05 A
- GSM7844340 A06 A
- GSM7844341 A07 A
- GSM7844342 A08 A
- GSM7844343 A09 A
- GSM7844344 A10 A
- GSM7844345 A11 A
- GSM7844346 A12 A
- GSM7844347 A13 A
- GSM7844348 A14 A
- GSM7844349 A15 A
- GSM7844350 A16 A
- GSM7844351 A17 A
- GSM7844352 A18 A
- GSM7844353 A19 A
- GSM7844354 A20 A
- GSM7844355 A21 A
- GSM7844356 A22 A
- GSM7844357 A23 A
- GSM7844358 L01 L
- GSM7844359 L02 L
- GSM7844360 L03 L
- GSM7844361 L04 L
- GSM7844362 L05 L
- GSM7844363 L06 L
- GSM7844364 L07 L
- GSM7844365 L08 L
- GSM7844366 L09 L
- GSM7844367 L10 L
- GSM7844368 L11 L
- GSM7844369 L12 L
- GSM7844370 L13 L
- GSM7844371 L14 L
- GSM7844372 L15 L
- GSM7844373 L17 L
- GSM7844374 L18 L
+ 1 more — browse all 41 samples with per-sample file links →
- GSE261723 3M-Brazzein, a Natural Sugar Substitute, can Suppress Metabolic Disorders, NAFLD, and Depression-like Behaviors in Diabetic Mice 24 samples shares nafld
- GSE159911 “Bench-to-Bedside and Back” analysis of NAFLD model reveals common transcriptomic shifts between mouse and human during disease progression 152 samples shares nafld
- GSE221443 Effect of Activin A and Gpnmb on gene expression in NAFLD/NASH liver in C57BL/6J mice and gene expression change in C57BL/6J mice fed on sugar water-NAFLD/NASH diet compared with standard chow diet 15 samples shares nafld
- GSE225560 Divergent roles for caspase-8 and MLKL in high-fat diet induced obesity and NAFLD in mice 12 samples shares nafld
- GSE305214 Transcriptomic profiling of liver tissue from control, DHT-induced PCOS-NAFLD model, and baicalin-treated mice using RNA-seq 12 samples shares nafld
- GSE286570 RNA sequencing(RNA-Seq)in liver tissues from different exercise interventions in NAFLD mice 12 samples shares nafld
- GSE319035 P21+TREM2+-Senescent Macrophages Fuel Inflammaging and Metabolic Dysfunction-Associated Steatotic Liver Disease [NAFLD_time_course] 77 samples shares nafld
- GSE247323 Maternal indole supplementation protects offspring from NAFLD through altered microbiota- and AHR-mediated ceramide metabolism 40 samples shares nafld
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.