Iron-Dependent KDM4D Activity Controls the Quiescence-Activity Balance of MSCs via the PI3K-Akt-Foxo1 Pathway
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 13 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 13 samples: 13 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Iron-dependent KDM4D activity controls the quiescence-activity balance of MSCs via the PI3K-Akt-Foxo1 pathwayCellular and molecular life sciences : CMLS · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE245686_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1029564 and SRA study SRP467091. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 13 sample titles: 13 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7846921 MSC1, untreated
- GSM7846922 MSC2, untreated
- GSM7846923 MSC3, untreated
- GSM7846924 MSC1, DFO treatment
- GSM7846925 MSC2, DFO treatment
- GSM7846926 MSC3, DFO treatment
- GSM7846927 MSC1, KDM4D knockdown
- GSM7846928 MSC2, KDM4D knockdown
- GSM7846929 MSC3, KDM4D knockdown
- GSM7846930 MSC, KDM4D, untreated
- GSM7846931 MSC, H3K9me3, untreated
- GSM7846932 MSC, KDM4D, DFO treatment
- GSM7846933 MSC, H3K9me3, DFO treatment
- GSE245684 Iron-Dependent KDM4D Activity Controls the Quiescence-Activity Balance of MSCs via the PI3K-Akt-Foxo1 Pathway [RNA-Seq] 9 samples shares kdm4d, quiescence-activity, iron-dependent, pi3k-akt-foxo1, activity, controls, balance, mscs
- GSE245685 Iron-Dependent KDM4D Activity Controls the Quiescence-Activity Balance of MSCs via the PI3K-Akt-Foxo1 Pathway [CUT&Tag] 4 samples shares kdm4d, quiescence-activity, iron-dependent, pi3k-akt-foxo1, activity, controls, balance, mscs
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.